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Primary spinal epidural rhabdomyosarcoma: a case report and review of the literature

Khalatbari, Mahmoud Reza and Jalaeikhoo, Hassan and Hamidi, Mehrdokht and Moharamzad, Yashar (2012) Primary spinal epidural rhabdomyosarcoma: a case report and review of the literature. Child's Nervous System, 28 (11). pp. 1977-1980. ISSN 0256-7040

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Primary intraspinal sarcomas are very rare in children. Rhabdomyosarcoma (RMS) is a highly aggressive and rapidly growing sarcoma with skeletal origin that occasionally appears in the spinal epidural space. We report a 13-year-old girl who presented with back pain, progressive paraparesis, and urinary retention. She had muscular weakness in her lower extremities and absent deep tendon reflex. An epidural dumbbell-shape mass at T11-T12 level was observed on MRI. The patient underwent T12 hemilaminectomy, partial T11 hemilaminectomy, and right facetectomy. A large, firm, dark-red vascular epidural tumor was found compressing the cord. The tumor which extended to intracanal and foraminal parts was removed completely. Histopathological examination revealed undifferentiated small round and oval tumoral cells. Immunohistochemical staining was positive for vimentin, desmin, and myogenin. The final diagnosis was alveolar RMS. She received radiotherapy and chemotherapy by vincristine, actinomycin-D, doxorubicin, and ifosfamide. The patient was in good condition with no tumor recurrence or metastasis at the 1-year follow-up.

Item Type: Article
Subjects: W Health professions
WX Hospital and other health Facilities
Depositing User: ePrint Admin Admin
Date Deposited: 02 Jul 2013 06:33
Last Modified: 02 Jul 2013 06:33

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